New Delhi Tuberculosis Centre was established in 1940 as a grantee institute of Government of India (Ministry of Health & Family Welfare). In 1951, it was upgraded as the first TB Demonstration cum Training Centre in the country with the assistance of WHO, UNICEF and Government of India.  In 1966, the Centre became a referral institute for tuberculosis patients.  The patients from all parts of country who are referred at the Centre were given diagnostic and treatment facilities. 

In the year 1997, New Delhi Tuberculosis Centre joined hands in implementation of DOTS strategy under RNTCP.  At this time, the Centre was one of the 10 chest clinics of Delhi who covered a population of about 0.5 million spread over an area of 15 sq. km. mainly in walled city of Delhi.

In the year 2005, the Central TB Division has designed New Delhi TB Centre as State TB Training & Demonstration Centre and Intermediate Reference Laboratory for Delhi State in addition to functioning as referral Centre for patients of pulmonary diseases and tuberculosis.

In the year 2015, the Centre has celebrated Platinum Jubilee year of its establishment. For this, monthly patients’ care related activities have been planned and executed.

The Centre has a Managing Committee which oversees the smooth functioning of New Delhi TB Centre. The Managing Committee has general control of the affairs of the Centre and have authority to do, exercise and perform all the powers, acts and deeds for the planning, establishment and running of the Centre. The committee consists of members from Ministry of Health & FW, Delhi Government and Corporations, TB Association of India and other NGOs. For smooth running of the Centre, the Ministry of Health & Family Welfare (CCD) allot the grant in aid to the Centre every financial year.